Reds caretaker manager Glyn Hodges will be forced into several changes for the trip to Vale Park.
Injuries have left the Tykes with only 18 fit players to choose from.
Mitch Ward, Chris Morgan, Mike Sheron, Brian O’Callaghan, Kevin Betsy, Paul Gibbs, Carl Barrowclough, Ashley Scothern and James Dudgeon are all set to miss out through injury.
Mike Flynn, Isaiah Rankin and Kevin Dixon are also unavailable.
Mitch Ward is still not fit enough to make the trip after his long lay-off despite playing 45 minutes in the Reserves in midweek.
It could have been worse for Hodges though as Steve Hayward and Gary Jones have shaken off injuries and are likely to start.